A man, who is in his 40s, suffered a suspected head injury.
The second patient is a teenage boy, who sustained suspected pelvic and arm injuries.
The Sunshine Coast RACQ CareFlight Rescue helicopter responded to the accident around 3.30pm.
Both patients were taken by QAS road ambulance to the Childers Showground, where the helicopter landed.
The man in his 40s was airlifted to Bundaberg Base Hospital in a stable condition.
CareFlight’s Flight Intensive Care Paramedic accompanied the teenager by road ambulance to Bundaberg Base Hospital.
He also travelled in a stable condition.