The two passengers sustained suspected lower limb injuries and suspected neurological conditions.
They were transported together to the Toowoomba Base Hospital in a stable condition.
A third passenger was also in the vehicle but she did not require airlifting.
The Toowoomba-based RACQ LifeFlight Rescue helicopter was tasked to the incident at approximately 7.30pm last night.
Yesterday the Toowoomba-based RACQ LifeFlight Rescue helicopter had the busiest day of its month, flying seven back to back missions.