The Toowoomba-based RACQ LifeFlight Rescue helicopter was called to the accident scene at Kents Lagoon, just after 8pm.
The daughter of one of the drivers, a 25-year-old woman, was airlifted by the RACQ LifeFlight Rescue helicopter with pelvic and internal injuries.
She was flown to the Princess Alexandra Hospital in a stable condition.
The Queensland Government (QG) Air rescue helicopter was first on the scene and airlifted the passenger of the second car, a 27-year-old woman, to the Royal Brisbane and Women’s Hospital with severe chest injuries.
The two drivers, a 22-year-old man and a 57-year-old woman, were transported by Queensland Ambulance Service (QAS) road ambulance to Ipswich Hospital with abdominal injuries.
The cause of the crash is unknown.
2016-17 was a record year for the Toowoomba-based RACQ LifeFlight Rescue helicopter which flew 609 lifesaving missions costing $7.6 million.
Last year was also a record year for LifeFlight for lifesaving missions throughout Queensland with its aeromedical crews, community helicopters and Air Ambulance jets performing a record 5,342 missions throughout Queensland and around the world.
LifeFlight is a community-based charity funded and supported by the LifeFlight Foundation
To support the LifeFlight Foundation visit:www.lifeflightfoundation.org.au