The Bundaberg based crew were tasked to the accident South of Gladstone on Gladstone-Monto Road at 11:30 this morning.
It is reported a convoy of eight motorcycles were rounding a bend when the lead motorcycle and an oncoming motor vehicle collided, with a subsequent two motorcycles becoming involved in the crash.
CareFlight transported a Gladstone husband and wife suffering from abrasions and possible fractures to Bundaberg hospital. They both travelled in a stable condition.
A third patient was airlifted to Rockhampton Hospital by another helicopter rescue provider.